Journal article
Development of an in vitro assay and demonstration of Plasmodium berghei liver-stage inhibition by TRAP-specific CD8+ T cells
- Abstract:
-
The development of an efficacious vaccine against the Plasmodium parasite remains a top priority. Previous research has demonstrated the ability of a prime-boost virally vectored sub-unit vaccination regimen, delivering the liver-stage expressed malaria antigen TRAP, to produce high levels of antigen-specific T cells. The liver-stage of malaria is the main target of T cell-mediated immunity, yet a major challenge in assessing new T cell inducing vaccines has been the lack of a suitable pre-cl...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Bibliographic Details
- Publisher:
- Public Library of Science
- Journal:
- PloS one More from this journal
- Volume:
- 10
- Issue:
- 3
- Pages:
- e0119880
- Publication date:
- 2015-01-01
- DOI:
- EISSN:
-
1932-6203
- ISSN:
-
1932-6203
Item Description
- Language:
- English
- Pubs id:
-
pubs:516939
- UUID:
-
uuid:2db2e5a8-e34d-41ee-84ae-1783b807f4b1
- Local pid:
- pubs:516939
- Source identifiers:
-
516939
- Deposit date:
- 2015-12-03
Terms of use
- Copyright holder:
- Longley et al
- Copyright date:
- 2015
- Notes:
- Copyright 2015 Longley et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
- Licence:
- CC Attribution (CC BY)
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