Association between telomere length and risk of cancer and non-neoplastic diseases: A Mendelian randomization study.
The causal direction and magnitude of the association between telomere length and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility of observational studies to confounding and reverse causation.
To conduct a Mendelian randomization study, using germline genetic variants as instrumental variables, to appraise the causal relevance of telomere length for risk of cancer and non-neoplastic diseases.
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- Peer review status:
- Peer reviewed
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- American Medical Association Publisher's website
- JAMA Oncology Journal website
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- Copyright holder:
- American Medical Association
- Copyright date:
- Copyright 2017 American Medical Association. All rights reserved.
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