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Recent genetic findings in schizophrenia and their therapeutic relevance.

Abstract:

Over 100 loci are now associated with schizophrenia risk as identified by single nucleotide polymorphisms (SNPs) in genome-wide association studies. These findings mean that 'genes for schizophrenia' have unquestionably been found. However, many questions remain unanswered, including several which affect their therapeutic significance. The SNPs individually have minor effects, and even cumulatively explain only a modest fraction of the genetic predisposition. The remainder likely results from...

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Publisher copy:
10.1177/0269881114553647

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Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Role:
Author
Journal:
Journal of psychopharmacology (Oxford, England)
Publication date:
2014-10-01
DOI:
EISSN:
1461-7285
ISSN:
0269-8811
Source identifiers:
487274
Language:
English
Keywords:
Pubs id:
pubs:487274
UUID:
uuid:f6ede38c-a079-451c-87ff-5e52cf2ad1df
Local pid:
pubs:487274
Deposit date:
2014-10-23

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