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Thesis

An fMRI study on the effects of the dopamine & noradrenaline reuptake inhibitor bupropion on reward processing in depressed individuals

Abstract:

Anhedonia, the loss of pleasure or motivation for usually enjoyable activities and rewards, is an established cardinal symptom in Major Depressive Disorder (MDD) whose underlying pathophysiology is not well-understood, and which lacks specific efficacious treatments. This thesis investigates the effects that bupropion, a dual reuptake inhibitor of dopamine and noradrenaline, has on the neural substrates implicated in reward processing amongst clinically depressed individuals compared to un...

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Division:
MSD
Department:
Psychiatry
Research group:
Psychopharmacology & Emotion Research Laboratory
Oxford college:
St Cross College
Role:
Author

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Role:
Supervisor
Role:
Supervisor
Role:
Examiner
Role:
Examiner
Type of award:
MSc by Research
Level of award:
Masters
Awarding institution:
University of Oxford

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