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SARS-CoV-2 RNA detected in blood products from patients with COVID-19 is not associated with infectious virus

Abstract:

Background: Laboratory diagnosis of SARS-CoV-2 infection (the cause of COVID-19) uses PCR to detect viral RNA (vRNA) in respiratory samples. SARS-CoV-2 RNA has also been detected in other sample types, but there is limited understanding of the clinical or laboratory significance of its detection in blood.

Methods: We undertook a systematic literature review to assimilate the evidence for the frequency of vRNA in blood, and to identify associated clinical characteristics. We performe...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.12688/wellcomeopenres.16002.2

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Role:
Author
ORCID:
0000-0002-0860-0831
Publisher:
F1000Research Publisher's website
Journal:
Wellcome Open Research Journal website
Volume:
5
Article number:
181
Publication date:
2020-07-29
Acceptance date:
2020-10-12
DOI:
EISSN:
2398-502X
Language:
English
Keywords:
Pubs id:
1123229
Local pid:
pubs:1123229
Deposit date:
2020-10-22

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