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Thesis

Addressing the immunological barriers to regenerative medicine: differentiation and characterisation of dendritic cells derived from induced pluripotent stem cells

Abstract:

Induced pluripotent stem cells (iPS cells) have shown great promise in the newly-developing field of regenerative medicine. Recently, however, there have been conflicting reports regarding their immunogenicity, even when derived in an autologous fashion, due to the ectopic expression of certain developmental antigens. Dendritic cells (DC) are professional antigen presenting cells and therefore serve as potential tools for modulating the immune response, particularly with respect to accepta...

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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Oxford college:
St Hilda's College
Role:
Author

Contributors

Role:
Supervisor
Publication date:
2013
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:f0fa4537-c020-405a-9d0e-5f83e5bedb4d
Deposit date:
2016-11-15

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