Working paper
The deubiquitylase USP9X controls ribosomal stalling
- Abstract:
-
When a ribosome stalls during translation, it runs the risk of collision with a trailing ribosome. Such an encounter leads to the formation of a stable di-ribosome complex, which needs to be resolved by a dedicated machinery. The initial stalling and the subsequent resolution of di-ribosomal complexes requires activity of Makorin and ZNF598 ubiquitin E3 ligases respectively, through ubiquitylation of the eS10 and uS10 sub-units of the ribosome. It is common for the stability of RING E3 ligase...
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- Publication status:
- Published
- Peer review status:
- Not peer reviewed
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Bibliographic Details
- Publisher:
- Cold Spring Harbor Publisher's website
- Publication date:
- 2020-04-17
- DOI:
Item Description
- Language:
- English
- Pubs id:
-
1102328
- Local pid:
- pubs:1102328
- Deposit date:
- 2020-04-29
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- Copyright date:
- 2020
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