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Journal article

Autoantibodies against neurologic antigens in nonneurologic autoimmunity

Abstract:

The aim of this study was to test whether autoantibodies against neurologic surface Ags are found in nonneurologic autoimmune diseases, indicating a broader loss of tolerance. Patient and matched healthy donor (HD) sera were derived from four large cohorts: 1) rheumatoid arthritis (RA) (n = 194, HD n = 64), 2) type 1 diabetes (T1D) (n = 200, HD n = 200), 3) systemic lupus erythematosus (SLE) (n = 200, HD n = 67; neuro-SLE n = 49, HD n = 33), and 4) a control cohort of neurologic autoimmunity ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.4049/jimmunol.1801295

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
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Role:
Author
ORCID:
0000-0002-0107-4103
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Publisher:
American Association of Immunologists Publisher's website
Journal:
Journal of Immunology Journal website
Volume:
202
Issue:
8
Pages:
2210-2219
Publication date:
2019-04-08
Acceptance date:
2019-02-01
DOI:
EISSN:
1550-6606
ISSN:
0022-1767
Pmid:
30824481
Language:
English
Pubs id:
pubs:980916
UUID:
uuid:eed30b2a-1587-48f7-818c-8400a2ec34e3
Local pid:
pubs:980916
Deposit date:
2019-04-25

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