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Thesis

The contribution of the systemic inflammatory response to the outcome of spinal cord injury

Abstract:

Non-resolving inflammation in the spinal cord following traumatic injury causes the progressive destruction of neuronal tissue, which exacerbates functional deficits. However, therapy targeting inflammation within the spinal cord has, to date, generated equivocal results, and there remains no clinically approved pharmacological intervention for spinal cord injury (SCI). Therefore, there is an immediate need to identify novel therapeutic targets. Traumatic central nervous system injuries, incl...

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Division:
MSD
Department:
Pharmacology
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
Pharmacology
Sub department:
Pharmacology
Oxford college:
Somerville College
Role:
Supervisor
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM - Investigative Medicine Division
Research group:
Buchan
Oxford college:
Somerville College
Role:
Supervisor
Institution:
University of Oxford
Division:
College Only
Research group:
Stoke Mandeville Spinal Research
Oxford college:
Harris Manchester College
Role:
Examiner
Institution:
King's College London
Role:
Examiner
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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