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Sex and death: the effects of innate immune factors on the sexual reproduction of malaria parasites

Abstract:

Malaria parasites must undergo a round of sexual reproduction in the blood meal of a mosquito vector to be transmitted between hosts. Developing a transmission-blocking intervention to prevent parasites from mating is a major goal of biomedicine, but its effectiveness could be compromised if parasites can compensate by simply adjusting their sex allocation strategies. Recently, the application of evolutionary theory for sex allocation has been supported by experiments demonstrating that malar...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.ppat.1001309

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Institution:
University of Edinburgh
Department:
Institutes of Evolution,Immunology and Infection Research
Role:
Author
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Institution:
"University of Oxford", "Instituto Gylbenkian de Ciência, Oeiras, Portugal"
Department:
Mathematical,Physical & Life Sciences Division - Zoology
Role:
Author
More by this author
Institution:
University of Edinburgh
Department:
Institutes of Evolution,Immunology and Infection Research
Role:
Author
More by this author
Institution:
"Instituto Gylbenkian de Ciência, Oeiras, Portugal", "University of Oxford"
Oxford college:
Balliol College
Role:
Author
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Institution:
University of Edinburgh
Department:
Centre for Immunity,Infection and Evolution
Role:
Author
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Funding agency for:
Andy Gardner
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Funding agency for:
Sarah E. Reece
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS Pathogens Journal website
Volume:
7
Issue:
3
Pages:
Article: e1001309
Publication date:
2011-03-05
DOI:
EISSN:
1553-7374
ISSN:
1553-7366
URN:
uuid:ec7d2713-3770-454a-9746-52457d4b984f
Local pid:
ora:5176
Language:
English
Keywords:
Subjects:

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