Journal article
Hippocampal acetylcholine depletion has no effect on anxiety, spatial novelty preference, or differential reward for low rates of responding (DRL) performance in rats
- Abstract:
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We investigated the role of the septo-hippocampal cholinergic projection in anxiety, spatial novelty preference, and differential reward for low rates of responding (DRL) performance. Cholinergic neurons of the rat medial septum (MS) and the vertical limb of the diagonal band of Broca (VDB) were lesioned using the selective immunotoxin, 192 IgG-saporin. Rats were then tested on several behavioral tests previously shown to be sensitive to either (a) hippocampal lesions or (b) nonselective MS/V...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, 347.2KB)
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- Publisher copy:
- 10.1037/bne0000072
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Authors
Funding
Bibliographic Details
- Publisher:
- American Psychological Association Publisher's website
- Journal:
- Behavioral Neuroscience Journal website
- Volume:
- 129
- Issue:
- 4
- Pages:
- 491-501
- Place of publication:
- United States
- Publication date:
- 2015-08-01
- Acceptance date:
- 2015-04-22
- DOI:
- EISSN:
-
1939-0084
- ISSN:
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0735-7044
- Pmid:
-
26214215
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
536087
- Local pid:
- pubs:536087
- Deposit date:
- 2020-02-14
Terms of use
- Copyright holder:
- McHugh et al.
- Copyright date:
- 2015
- Rights statement:
- © 2015 The Author(s). This article has been published under the terms of the Creative Commons Attribution License
- Licence:
- CC Attribution (CC BY)
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