Journal article icon

Journal article

How threshold behaviour affects the use of subgraphs for network comparison

Abstract:

Motivation: A wealth of protein-protein interaction (PPI) data has recently become available. These data are organized as PPI networks and an efficient and biologically meaningful method to compare such PPI networks is needed. As a first step, we would like to compare observed networks to established network models, under the aspect of small subgraph counts, as these are conjectured to relate to functional modules in the PPI network. We employ the software tool GraphCrunch with the Graphle...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1093/bioinformatics/btq386

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Research group:
OCISB/DTC Systems Biology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Statistics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Research group:
OCISB/DTC Systems Biology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Research group:
OCISB/DTC Systems Biology
Role:
Author

Contributors

Systems Biology Doctoral Training Center More from this funder
Oxford Center for Integrated Systems Biology More from this funder
Fundação para a Ciência e a Tecnologia More from this funder
Publisher:
Oxford University Press Publisher's website
Journal:
Bioinformatics Journal website
Volume:
26
Issue:
18
Pages:
i611-i617
Publication date:
2010-01-01
DOI:
EISSN:
1460-2059
ISSN:
1367-4803
Language:
English
Keywords:
Subjects:
UUID:
uuid:e8baa813-e09f-4542-bf10-1954eee87bad
Local pid:
ora:5908
Deposit date:
2011-11-15

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP