Journal article icon

Journal article

C-H cyanation of 6-ring N-containing heteroaromatics

Abstract:

Heteroaromatic nitriles are important compounds in drug discovery, both for their prevalence in the clinic and due to the diverse range of transformations they can undergo. As such, efficient and reliable methods to access them have the potential for far-reaching impact across synthetic chemistry and the biomedical sciences. Herein, we report an approach to heteroaromatic C-H cyanation through triflic anhydride activation, nucleophilic addition of cyanide, followed by elimination of trifluoro...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1002/chem.201703931

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Chemistry; Organic Chemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Chemistry; Organic Chemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Chemistry; Organic Chemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Chemistry; Organic Chemistry
Role:
Author
Expand authors...
John Fell Fund More from this funder
Publisher:
Wiley Publisher's website
Journal:
Chemistry - A European Journal Journal website
Volume:
23
Issue:
59
Pages:
14733-14737
Publication date:
2017-08-23
Acceptance date:
2017-08-22
DOI:
EISSN:
1521-3765
ISSN:
0947-6539
Pmid:
28833674
Language:
English
Keywords:
Pubs id:
pubs:724085
UUID:
uuid:e867361a-2ddf-46bf-a8c6-e13bb629866e
Local pid:
pubs:724085
Deposit date:
2017-10-06

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP