Journal article
C-H cyanation of 6-ring N-containing heteroaromatics
- Abstract:
-
Heteroaromatic nitriles are important compounds in drug discovery, both for their prevalence in the clinic and due to the diverse range of transformations they can undergo. As such, efficient and reliable methods to access them have the potential for far-reaching impact across synthetic chemistry and the biomedical sciences. Herein, we report an approach to heteroaromatic C-H cyanation through triflic anhydride activation, nucleophilic addition of cyanide, followed by elimination of trifluoro...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
John Fell Fund
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UCB Pharma
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Bibliographic Details
- Publisher:
- Wiley Publisher's website
- Journal:
- Chemistry - A European Journal Journal website
- Volume:
- 23
- Issue:
- 59
- Pages:
- 14733-14737
- Publication date:
- 2017-08-23
- Acceptance date:
- 2017-08-22
- DOI:
- EISSN:
-
1521-3765
- ISSN:
-
0947-6539
- Pmid:
-
28833674
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:724085
- UUID:
-
uuid:e867361a-2ddf-46bf-a8c6-e13bb629866e
- Local pid:
- pubs:724085
- Deposit date:
- 2017-10-06
Terms of use
- Copyright holder:
- © 2017 Wiley-VCH Verlag GmbH & Co KGaA, Weinheim
- Copyright date:
- 2017
- Notes:
- This is an open access article under the terms of the Creative Commons At-tribution License, which permits use, distribution and reproduction in any medium, provided the original workis properly cited
- Licence:
- CC Attribution (CC BY)
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