Thesis
A method for the identification of biological pathways
- Abstract:
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Plenty of gene variants have been associated with disease, indicating widespread genetic heterogeneity, which leaves the molecular basis of complex diseases unclear. However, it is widely postulated that the products of genes whose mutations are implicated in the same disease function together in the same biological pathways and it is the disruption of these pathways that underlies the disease. Such pathways are not well defined and their identification could help elucidate disease mechanisms...
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Authors
Contributors
+ Webber, C
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Supervisor
+ Ponting, C
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Supervisor
Funding
Bibliographic Details
- Publication date:
- 2014
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
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uuid:e7079080-a814-431a-badd-35080f5a2825
- Local pid:
- ora:12514
- Deposit date:
- 2016-07-05
Terms of use
- Copyright holder:
- Honti, F
- Copyright date:
- 2014
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