Journal article
Inhaled budesonide for COVID-19 in people at higher risk of adverse outcomes in the community: interim analyses from the PRINCIPLE trial
- Abstract:
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BACKGROUND: Inhaled budesonide has shown efficacy for treating COVID-19 in the community but has not yet been tested in effectiveness trials.
METHODS: We performed a multicenter, open-label, multi-arm, adaptive platform randomized controlled trial involving people aged ≥65 years, or ≥50 years with comorbidities, and unwell ≤14 days with suspected COVID-19 in the community (PRINCIPLE). Participants were randomized to usual care, usual care plus inha...
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- Publication status:
- Published
- Peer review status:
- Not peer reviewed
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- Files:
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(Submitted manuscript under review, 717.3KB)
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- Publisher copy:
- 10.1101/2021.04.10.21254672
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Authors
Contributors
+ PRINCIPLE Collaborative Group
Division:
MSD
Oxford college:
Trinity College
Role:
Contributor
Bibliographic Details
- Publisher:
- Cold Spring Harbor Laboratory Publisher's website
- Journal:
- medRxiv Journal website
- Publication date:
- 2021-04-12
- DOI:
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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1171185
- Local pid:
- pubs:1171185
- Deposit date:
- 2021-05-10
Terms of use
- Copyright holder:
- Yu et al.
- Copyright date:
- 2021
- Rights statement:
- The copyright holder for this preprint is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.
- Licence:
- CC Attribution (CC BY)
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