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Body-mass index and all-1 cause mortality: Individual-participant-data meta-analysis of 239 prospective studies in four continents

Abstract:
Background: Overweight and obesity are increasing worldwide. To help assess their relevance to mortality in different populations we conducted individual-participant-data meta-analyses of the prospective studies of body mass index (BMI), limiting confounding and reverse causality by restricting analyses to never-smokers and excluding prior disease and the first 5 years of follow- up. Methods: Of 10,625,411 participants in Asia, Australia/New Zealand, Europe... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1016/S0140-6736(16)30175-1

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Institution:
University of Oxford
Department:
Oxford, MSD, Obstetrics and Gynaecology
Role:
Author
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Institution:
University of Oxford
Department:
Oxford, MSD, NDM Experimental Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Obstetrics and Gynaecology
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Nuffield Department of Population Health, Clinical Trial Service Unit
Role:
Author
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Medical Research Council More from this funder
British Heart Foundation More from this funder
National Institute for Health Research More from this funder
National Institutes of Health More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Lancet Journal website
Volume:
388
Issue:
10046
Pages:
776-786
Publication date:
2016-07-13
Acceptance date:
2016-04-01
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
URN:
uuid:e5e3b775-c5c6-4c14-8b23-0fede9c743b6
Source identifiers:
616637
Local pid:
pubs:616637

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