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Huge (14-, 21-, 28-, 35-, 56- and 70-membered ring) macrocyclic lactams - a novel family of carbopeptoid-cyclodextrins

Abstract:
Hydrogenation of linear ω-azido-pentafluorophenyl esters gives cyclic peptides containing 14-, 21-, 28-, 35-, 56- and 70-membered ring lactams from oligomers derived from ε-amino acids in excellent to moderate yields with a lack of racemisation during the cyclisation step. © 2003 Elsevier Ltd. All rights reserved.
Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
Role:
Author
Journal:
TETRAHEDRON LETTERS
Volume:
45
Issue:
1
Pages:
157-162
Publication date:
2004-01-01
DOI:
ISSN:
0040-4039
URN:
uuid:e4ed54d2-7410-4119-94e6-da81444c23f3
Source identifiers:
38949
Local pid:
pubs:38949

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