Journal article
Myeloma cells down-regulate adiponectin in bone marrow adipocytes via TNF-alpha
- Abstract:
-
Multiple myeloma is caused by abnormal plasma cells that accumulate in the bone marrow and interact with resident cells of the bone microenvironment to drive disease progression and development of an osteolytic bone disease. Bone marrow adipocytes (BMAds) are emerging as having important endocrine functions that can support myeloma cell growth and survival. However, how BMAds respond to infiltrating tumor cells remains poorly understood. Using the C57BL/KaLwRij murine model of myeloma, bone m...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
International Myeloma Foundation
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Bibliographic Details
- Publisher:
- Wiley Publisher's website
- Journal:
- Journal of Bone and Mineral Research Journal website
- Volume:
- 35
- Issue:
- 5
- Pages:
- 942-955
- Publication date:
- 2020-01-16
- Acceptance date:
- 2019-12-14
- DOI:
- EISSN:
-
1523-4681
- ISSN:
-
0884-0431
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:1078141
- UUID:
-
uuid:e3be2939-5a2b-4923-9393-fc97d4f734cc
- Local pid:
- pubs:1078141
- Source identifiers:
-
1078141
- Deposit date:
- 2019-12-17
Terms of use
- Copyright holder:
- Morris, EV et al.
- Copyright date:
- 2020
- Rights statement:
- © 2019 The Authors. Journal of Bone and Mineral Research published by American Society for Bone and Mineral Research. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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