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Journal article

Ct threshold values, a proxy for viral load in community SARS-CoV-2 cases, demonstrate wide variation across populations and over time

Abstract:

Background:

Information on SARS-CoV-2 in representative community surveillance is limited, particularly cycle threshold (Ct) values (a proxy for viral load).

Methods:

We included all positive nose and throat swabs 26 April 2020 to 13 March 2021 from the UK’s national COVID-19 Infection Survey, tested by RT-PCR for the N, S, and ORF1ab genes. We investigated predictors of median Ct value using quantile regression.

Results:

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.7554/elife.64683

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
ORCID:
0000-0002-0412-8509
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
More by this author
Role:
Author
ORCID:
0000-0001-8131-4893
Expand authors...
Publisher:
eLife Sciences Publications Publisher's website
Journal:
eLife Journal website
Volume:
10
Article number:
e64683
Publication date:
2021-07-12
Acceptance date:
2021-07-06
DOI:
EISSN:
2050-084X
Language:
English
Keywords:
Pubs id:
1186487
Local pid:
pubs:1186487
Deposit date:
2021-07-15

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