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Study on genetic structure differences and adjustment strategies in different areas of China

Abstract:

Objective: To describe the genetic structure of populations in different areas of China, and explore the effects of different strategies to control the confounding factors of the genetic structure in cohort studies.

Methods: By using the genome-wide association study (GWAS) on data of 4 500 samples from 10 areas of the China Kadoorie Biobank (CKB), we performed principal components analysis to extract the first and second principal components of the...

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Publication status:
Published
Peer review status:
Peer reviewed

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Grant:
2016YFC0900500, 2016YFC0900501, 2016YFC0900504
Publisher:
Wanfang Data Co. Ltd. Publisher's website
Journal:
Chinese Journal of Epidemiology Journal website
Volume:
40
Issue:
1
Pages:
20-25
Publication date:
2019-03-08
Acceptance date:
2018-12-05
DOI:
ISSN:
0254-6450
Pmid:
30669726
Pubs id:
pubs:965980
UUID:
uuid:e06af772-4555-43e2-bc1b-89206f114def
Source identifiers:
965980
Local pid:
pubs:965980

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