Journal article
Effects of anacetrapib in patients with atherosclerotic vascular disease
- Abstract:
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BACKGROUND Patients with atherosclerotic vascular disease remain at high risk for cardiovascular events despite effective statin-based treatment of low-density lipoprotein (LDL) cholesterol levels. The inhibition of cholesteryl ester transfer protein (CETP) by anacetrapib reduces LDL cholesterol levels and increases high-density lipoprotein (HDL) cholesterol levels. However, trials of other CETP inhibitors have shown neutral or adverse effects on cardiovascular outcomes.
METHODS We...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 252.8KB)
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- Publisher copy:
- 10.1056/NEJMoa1706444
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Authors
Funding
Merck
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Clinical Research Network
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Medical Research Council
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Bibliographic Details
- Publisher:
- Massachusetts Medical Society Publisher's website
- Journal:
- New England Journal of Medicine Journal website
- Publication date:
- 2017-08-28
- Acceptance date:
- 2017-08-14
- DOI:
- EISSN:
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1533-4406
- ISSN:
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0028-4793
- Source identifiers:
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729362
Item Description
- Keywords:
- Pubs id:
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pubs:729362
- UUID:
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uuid:df07e2b2-a291-4296-89a1-0f307517a1d4
- Local pid:
- pubs:729362
- Deposit date:
- 2017-09-20
Terms of use
- Copyright holder:
- Massachusetts Medical Society
- Copyright date:
- 2017
- Notes:
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This is the version of record of the article. The final version is
available online from Massachusetts Medical Society at: https://doi.org/10.1056/NEJMoa1706444
If you are the owner of this record, you can report an update to it here: Report update to this record