Journal article
Multi-population genomic analysis of malaria parasites indicates local selection and differentiation at the gdv1 locus regulating sexual development
- Abstract:
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Parasites infect hosts in widely varying environments, encountering diverse challenges for adaptation. To identify malaria parasite genes under locally divergent selection across a large endemic region with a wide spectrum of transmission intensity, genome sequences were obtained from 284 clinical Plasmodium falciparum infections from four newly sampled locations in Senegal, The Gambia, Mali and Guinea. Combining these with previous data from seven other sites in West Africa enabled a multi-p...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 2.7MB)
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- Publisher copy:
- 10.1038/s41598-018-34078-3
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Authors
Funding
Wellcome Trust
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+ Biotechnology and Biological Sciences Research Council (BBSRC)
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Grant:
LIDO studentship
+ Biotechnology and Biological Sciences Research Council
More from this funder
Grant:
LIDO studentship
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Bibliographic Details
- Publisher:
- Springer Nature Publisher's website
- Journal:
- Scientific Reports Journal website
- Volume:
- 8
- Issue:
- 2018
- Article number:
- 15763
- Publication date:
- 2018-10-25
- Acceptance date:
- 2018-10-11
- DOI:
- ISSN:
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2045-2322
- Pmid:
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30361631
- Source identifiers:
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1037107
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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pubs:1037107
- UUID:
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uuid:de229ed2-d0e2-4a4c-954c-935b7f362a84
- Local pid:
- pubs:1037107
- Deposit date:
- 2019-09-06
Terms of use
- Copyright date:
- 2018
- Notes:
- This is an open access article distributed under the terms of the Creative Commons Attribution Licence
- Licence:
- CC Attribution (CC BY)
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