Journal article
Combining simple blood tests to identify primary care patients with unexpected weight loss for cancer investigation: clinical risk score development, internal validation, and net benefit analysis
- Abstract:
-
Background
Unexpected weight loss (UWL) is a presenting feature of cancer in primary care. Existing research proposes simple combinations of clinical features (risk factors, symptoms, signs, and blood test data) that, when present, warrant cancer investigation. More complex combinations may modify cancer risk to sufficiently rule-out the need for investigation. We aimed to identify which clinical features can be used together to stratify patients with UWL based on the... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, 1.3MB)
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- Publisher copy:
- 10.1371/journal.pmed.1003728
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Authors
Funding
Department of Health
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Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS Medicine Journal website
- Volume:
- 18
- Issue:
- 8
- Article number:
- e1003728
- Place of publication:
- United States
- Publication date:
- 2021-08-31
- Acceptance date:
- 2021-07-12
- DOI:
- EISSN:
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1549-1676
- ISSN:
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1549-1277
- Pmid:
-
34464384
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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1193745
- Local pid:
- pubs:1193745
- Deposit date:
- 2021-12-06
Terms of use
- Copyright holder:
- Nicholson et al.
- Copyright date:
- 2021
- Rights statement:
- ©2021 Nicholson et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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