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Ankylosing spondylitis confers substantially increased risk of clinical spine fractures: a nationwide case-control study.

Abstract:

UNLABELLED: Ankylosing spondylitis (AS) leads to osteopenia/osteoporosis and spine rigidity. We conducted a case-control study and found that AS-affected patients have a 5-fold and 50 % increased risk of clinical spine and all clinical fractures, respectively. Excess risk of both is highest in the first years and warrants an early bone health assessment after diagnosis. INTRODUCTION: Ankylosing spondylitis (AS) is related to spine rigidity and reduced bone mass, but data on its impact on frac...

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Publication status:
Published

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Publisher copy:
10.1007/s00198-014-2939-3

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
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Publisher:
Springer-Verlag London Ltd
Journal:
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Volume:
26
Issue:
1
Pages:
85-91
Publication date:
2015-01-05
DOI:
EISSN:
1433-2965
ISSN:
0937-941X
URN:
uuid:d7c5c91a-8a73-4914-bdee-67127d978cc5
Source identifiers:
487470
Local pid:
pubs:487470

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