Journal article
Phase 3 efficacy analysis of a typhoid conjugate vaccine trial in Nepal
- Abstract:
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BACKGROUND
Salmonella Typhi is a major cause of fever in children in low- and middle-income countries. A typhoid conjugate vaccine (TCV) that was recently prequalified by the World Health Organization was shown to be efficacious in a human challenge model, but data from efficacy trials in areas where typhoid is endemic are lacking.
METHODS
In this phase 3, randomized, controlled trial in Lalitpur, Nepal, in which both the participants ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Version of record, pdf, 214.3KB)
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- Publisher copy:
- 10.1056/nejmoa1905047
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Authors
Funding
Bibliographic Details
- Publisher:
- Massachusetts Medical Society Publisher's website
- Journal:
- New England Journal of Medicine Journal website
- Volume:
- 381
- Issue:
- 23
- Pages:
- 2209-2218
- Publication date:
- 2019-12-05
- Acceptance date:
- 2019-09-23
- DOI:
- EISSN:
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1533-4406
- ISSN:
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0028-4793
- Pmid:
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31800986
- Source identifiers:
-
1076844
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:1076844
- UUID:
-
uuid:d0d7fd44-046d-42a5-9af7-dd3353c9c721
- Local pid:
- pubs:1076844
- Deposit date:
- 2019-12-07
Terms of use
- Copyright holder:
- Massachusetts Medical Society
- Copyright date:
- 2019
- Rights statement:
- © 2019 Massachusetts Medical Society.
- Notes:
- This is the publisher's version of the article. The final version is available online from the Massachusetts Medical Society at: https://doi.org/10.1056/NEJMoa1905047
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