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Journal article : Review

Home and away: The role of non-coding RNA in intracellular and intercellular DNA damage response

Abstract:

Non-coding RNA (ncRNA) has recently emerged as a vital component of the DNA damage response (DDR), which was previously believed to be solely regulated by proteins. Many species of ncRNA can directly or indirectly influence DDR and enhance DNA repair, particularly in response to double-strand DNA breaks, which may hold therapeutic potential in the context of cancer. These include long non-coding RNA (lncRNA), microRNA, damage-induced lncRNA, DNA damage response small RNA, and DNA:RNA hybrid s...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.3390/genes12101475

Authors


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Role:
Author
ORCID:
0000-0002-9309-2586
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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Oxford college:
Wadham College
Role:
Author
Publisher:
MDPI
Journal:
Genes More from this journal
Volume:
12
Issue:
10
Article number:
1475
Publication date:
2021-09-23
Acceptance date:
2021-09-21
DOI:
EISSN:
2073-4425
Pmid:
34680868
Language:
English
Keywords:
Subtype:
Review
Pubs id:
1203272
Local pid:
pubs:1203272
Deposit date:
2022-01-24

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