Journal article
The measles virus receptor SLAMF1 can mediate particle endocytosis
- Abstract:
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The signalling lymphocyte activation molecule F1 (SLAMF1) is both a microbial sensor and entry receptor for Measles virus (MeV). Herein, we describe a new role for SLAMF1 to mediate MeV endocytosis that is in contrast with the alternative, and generally accepted, model that MeV genome enters cells only after fusion at the cell surface. We demonstrated that MeV engagement of SLAMF1 induces dramatic but transient morphological changes, most prominently in the formation of membrane blebs, which ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 3.4MB)
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- Publisher copy:
- 10.1128/JVI.02255-16
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Authors
Funding
Medical Research Council
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Bibliographic Details
- Publisher:
- American Society for Microbiology Publisher's website
- Journal:
- Journal of Virology Journal website
- Volume:
- 91
- Issue:
- 7
- Pages:
- e02255-16
- Publication date:
- 2017-01-01
- Acceptance date:
- 2017-01-01
- DOI:
- EISSN:
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1098-5514
- ISSN:
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0022-538X
- Source identifiers:
-
675248
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:675248
- UUID:
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uuid:cdd1a6e0-7cc1-43c2-9574-0687a33335a9
- Local pid:
- pubs:675248
- Deposit date:
- 2017-02-03
Terms of use
- Copyright holder:
- Gonçalves-Carneiro et al
- Copyright date:
- 2017
- Notes:
- Copyright © 2017 Gonçalves-Carneiro et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.
- Licence:
- CC Attribution (CC BY)
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