Journal article icon

Journal article

CD161(+)CD4(+) T cells are enriched in the liver during chronic hepatitis and associated with co-secretion of IL-22 and IFN-γ.

Abstract:

Hepatitis C virus infection is a major cause of chronic liver disease. CD4(+) T cells play a key role in disease outcome. However, the critical functions and associated phenotypes of intrahepatic CD4(+) T cells are not well defined. We have previously shown that CD8(+) T cells expressing the C type lectin CD161 are highly enriched in the human liver, especially during chronic hepatitis. These cells are associated with a type 17 differentiation pattern and express cytokines including IL-17A, I...

Expand abstract

Actions


Access Document


Publisher copy:
10.3389/fimmu.2012.00346

Authors


Expand authors...
Journal:
Frontiers in immunology
Volume:
3
Issue:
NOV
Pages:
346
Publication date:
2012-01-01
DOI:
EISSN:
1664-3224
URN:
uuid:cc9769eb-d6d1-4366-8a76-593b9b13e552
Source identifiers:
365458
Local pid:
pubs:365458
Language:
English
Keywords:

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP