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Variation in follicle health and development in cultured cryopreserved ovarian cortical tissue: a study of ovarian tissue from patients undergoing fertility preservation

Abstract:

This study investigated how follicle health and development in human ovarian tissue cryopreserved for fertility preservation varied between patients before and after 6 d of in vitro culture. Ovarian tissue from 12 patients (9–25 years) was used. In 3 patients, a 1hr neutral red (NR) incubation was used to identify tissues with viable follicles. Tissues were fixed, sectioned and follicles staged and graded for health. Inter-patient differences were observed in the non-cultured tissue in the nu...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1080/14647273.2019.1616118

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Women's & Reproductive Health
Sub department:
Women's & Reproductive Health
Oxford college:
Jesus College
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Women's & Reproductive Health
Sub department:
Women's & Reproductive Health
Oxford college:
St Cross College
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Women's & Reproductive Health
Sub department:
Women's & Reproductive Health
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Women's & Reproductive Health
Sub department:
Women's & Reproductive Health
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Women's & Reproductive Health
Sub department:
Women's & Reproductive Health
Role:
Author
ORCID:
0000-0003-1798-976X
More from this funder
Funding agency for:
Bjarkadottir, B
Grant:
Doctoral Training Partnership: Oxford-MRC DTP
Publisher:
Taylor and Francis Publisher's website
Journal:
Human Fertility Journal website
Volume:
24
Issue:
3
Pages:
188-198
Publication date:
2019-05-23
Acceptance date:
2019-03-07
DOI:
EISSN:
1742-8149
ISSN:
1464-7273
Pmid:
31117847
Source identifiers:
1004520
Language:
English
Keywords:
Pubs id:
pubs:1004520
UUID:
uuid:caf70541-8390-4070-b7ca-9fe971834794
Local pid:
pubs:1004520
Deposit date:
2019-06-28

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