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A Model of the Spatially Dependent Mechanical Properties of the Axon During Its Growth

Abstract:

Neuronal growth is a complex process involving many intra- and extracellular mechanisms which are collaborating conjointly to participate to the development of the nervous system. More particularly, the early neocortical development involves the creation of a multilayered structure constituted by neuronal growth (driven by axonal or dendritic guidance cues) as well as cell migration. The underlying mechanisms of such structural lamination not only implies important biochemical changes at the ...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MPLS, Engineering Science
Role:
Author
Journal:
CMES-COMPUTER MODELING IN ENGINEERING and SCIENCES
Volume:
87
Issue:
5
Pages:
411-432
Publication date:
2012-10-05
ISSN:
1526-1492
URN:
uuid:ca9f13b5-3ecd-4b93-9550-04de790e7a4d
Source identifiers:
377835
Local pid:
pubs:377835

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