Journal article
A generative angular model of protein structure evolution
- Abstract:
-
Recently described stochastic models of protein evolution have demonstrated that the inclusion of structural information in addition to amino acid sequences leads to a more reliable estimation of evolutionary parameters. We present a generative, evolutionary model of protein structure and sequence that is valid on a local length scale. The model concerns the local dependencies between sequence and structure evolution in a pair of homologous proteins. The evolutionary trajectory between the tw...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
+ Spanish Ministry of Economy and Competitiveness
More from this funder
Funding agency for:
Garcia-Portugues, E
Grant:
MTM2016-76969-P
Bibliographic Details
- Publisher:
- Oxford University Press Publisher's website
- Journal:
- Molecular Biology and Evolution Journal website
- Publication date:
- 2017-04-27
- Acceptance date:
- 2017-04-14
- DOI:
- EISSN:
-
1537-1719
- ISSN:
-
0737-4038
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:689208
- UUID:
-
uuid:c51430ad-fab0-49e1-aba3-03f88da1268f
- Local pid:
- pubs:689208
- Source identifiers:
-
689208
- Deposit date:
- 2017-05-30
Terms of use
- Copyright holder:
- © Golden, et al 2017
- Copyright date:
- 2017
- Notes:
- This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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