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Pain trajectory defines knee osteoarthritis subgroups: a prospective observational study

Abstract:

Knee osteoarthritis (OA) is a heterogeneous disease, and identification of its subgroups/phenotypes can improve patient treatment and drug development. We aimed to identify homogeneous OA subgroups/phenotypes using pain development over time; to understand the interplay between pain and functional limitation in time course; and to investigate subgroups' responses to available pharmacological and surgical treatments. We used group-based trajectory modelling to identify pain trajectories in the...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1097/j.pain.0000000000001975

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
ORCID:
0000-0002-3452-3382
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
ORCID:
0000-0002-5172-512X
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Publisher:
Lippincott, Williams & Wilkins Publisher's website
Journal:
PAIN Journal website
Volume:
161
Issue:
12
Pages:
2841-2851
Publication date:
2020-06-24
Acceptance date:
2020-06-17
DOI:
EISSN:
1872-6623
ISSN:
0304-3959
Pmid:
32639366
Language:
English
Keywords:
Pubs id:
1115228
Local pid:
pubs:1115228
Deposit date:
2020-07-28

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