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Journal article

SARS-CoV-2 antibody prevalence, titres and neutralising activity in an antenatal cohort, United Kingdom, 14 April to 15 June 2020

Abstract:

SARS-CoV-2 IgG screening of 1,000 antenatal serum samples in the Oxford area, United Kingdom, between 14 April and 15 June 2020, yielded a 5.3% seroprevalence, mirroring contemporaneous regional data. Among the 53 positive samples, 39 showed in vitro neutralisation activity, correlating with IgG titre (Pearson's correlation p<0.0001). While SARS-CoV-2 seroprevalence in pregnancy cohorts could potentially inform population surveillance, clinical correlates of infection and immunity in pregn...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.2807/1560-7917.es.2020.25.41.2001721

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Institution:
University of Oxford
Division:
MSD
Sub department:
BH NDM STRATEGIC; BX POPULATION HEALTH; H6 CLINICAL TRIAL SERVICE UNIT
Role:
Author
ORCID:
0000-0001-5095-6367
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Publisher:
European Centre for Disease Prevention and Control Publisher's website
Journal:
Eurosurveillance Journal website
Volume:
25
Issue:
42
Publication date:
2020-10-22
Acceptance date:
2020-10-22
DOI:
EISSN:
1560-7917
ISSN:
1025-496X
Pmid:
33094717
Language:
English
Keywords:
Pubs id:
1139539
Local pid:
pubs:1139539
Deposit date:
2020-11-14

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