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Journal article

Colchicine for COVID-19 in adults in the community (PRINCIPLE): a randomised, controlled, adaptive platform trial

Abstract:

Objectives Colchicine has been proposed as a COVID-19 treatment, but its effect on time to recovery is unknown. We aimed to determine whether colchicine is effective at reducing time to recovery and COVID-19 related hospitalisations/deaths among people in the community. Design Prospective, multicentre, open-label, multi-arm, adaptive Platform Randomised Trial of Treatments in the Community for Epidemic and Pandemic Illnesses (PRINCIPLE). Setting National trial run remotely from a central tr...

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Publication status:
Not published
Peer review status:
Not peer reviewed

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Publisher copy:
10.1101/2021.09.20.21263828

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Oxford college:
Green Templeton College
Role:
Author
ORCID:
0000-0001-6072-1430
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author
ORCID:
0000-0003-0331-7364
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Oxford college:
Exeter College
Role:
Author
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Publisher:
Cold Spring Harbor Laboratory Press Publisher's website
Journal:
medRxiv Journal website
DOI:
Language:
English
Keywords:
Pubs id:
1195761
Local pid:
pubs:1195761
Deposit date:
2021-11-26

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