Thesis
Single cell analysis of the fibrotic landscape in Dupuytren's disease
- Abstract:
-
Fibrotic disorders represent some of the most devastating and poorly treated conditions in the Western World. Despite this, effective therapeutic interventions have yet to be identified for many of these conditions. A major barrier to identification of novel targets and successful clinical translation is a poor understanding of the myofibroblast-rich human fibrotic microenvironment, compounded by the dynamic nature of this ecosystem. Here, I use Dupuytren’s disease (DD), a localized fibrot...
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Authors
Contributors
+ Nanchahal, J
Role:
Supervisor
ORCID:
0000-0002-9579-9411
+ Furniss, D
Role:
Supervisor
ORCID:
0000-0003-2780-7173
Funding
Celgene-Oxford Fellowship
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Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- UUID:
-
uuid:bc01f849-0af7-4ad9-9ca0-0cf07baa1aa8
- Deposit date:
- 2020-01-29
Terms of use
- Copyright holder:
- Layton, T
- Copyright date:
- 2019
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