Journal article icon

Journal article

SARS-CoV-2 innate effector associations and viral load in early nasopharyngeal infection

Abstract:

COVID-19 causes severe disease with poor outcomes. We tested the hypothesis that early SARS-CoV-2 viral infection disrupts innate immune responses. These changes may be important for understanding subsequent clinical outcomes. We obtained residual nasopharyngeal swab samples from individuals who requested COVID-19 testing for symptoms at drive-through COVID-19 clinical testing sites operated by the University of Utah. We applied multiplex immunoassays, real-time polymerase chain reaction assa...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.14814/phy2.14761

Authors


More by this author
Role:
Author
ORCID:
0000-0003-0121-4847
More by this author
Role:
Author
ORCID:
0000-0002-9022-3157
More by this author
Role:
Author
ORCID:
0000-0001-8767-2149
More by this author
Role:
Author
ORCID:
0000-0002-5977-2350
NCI NIH HHS More from this funder
Publisher:
Wiley Open Access Publisher's website
Journal:
Physiological Reports Journal website
Volume:
9
Issue:
4
Article number:
e14761
Publication date:
2021-02-24
Acceptance date:
2021-01-24
DOI:
EISSN:
2051-817X
Pmid:
33625796

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP