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Thesis

Computational methods for light sheet fluorescence microscopy: towards a quantitative analysis of AVE migration in the mouse

Abstract:

Collective migration in epithelial tissues is required for many developmental processes, wound healing, and cancer, and is conserved across vertebrates. It is a process that has been difficult to study for 3D epithelia in vivo as the large timelapse datasets required present significant computational challenges for quantitative analysis. An important example of collective migration in an epithelial context is the migration of Anterior Visceral Endoderm (AVE) cells in the mouse embryo. From...

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Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Research group:
Srinivas
Oxford college:
Lincoln College
Role:
Author
ORCID:
0000-0001-6480-7768

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Research group:
Srinivas
Role:
Contributor, Supervisor
ORCID:
0000-0002-4892-7687
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Oxford Ludwig Institute
Research group:
Rittscher Group
Role:
Contributor
ORCID:
0000-0003-4463-1165
Institution:
University of Liverpool
Role:
Contributor
ORCID:
0000-0001-7395-2879
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Research group:
Rittscher Group
Oxford college:
Harris Manchester College
Role:
Supervisor
ORCID:
0000-0002-8528-8298
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Research group:
Srinivas
Oxford college:
Jesus College
Role:
Supervisor
ORCID:
0000-0001-5726-7791
More from this funder
Programme:
Chromosome and Developmental Biology Doctoral Training Centre
Funding agency for:
Hathrell, H
Grant:
109100/Z/15/Z
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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