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Novel approaches towards characterising the HIV reservoir: A combined microfluidic and target enrichment approach

Abstract:

The latent reservoir in human immunodeficiency virus (HIV) infection is a small population of long-lived infected cells that remain quiescent during suppressive antiretroviral therapy (ART). This reservoir is widely considered to be the major barrier to HIV cure, as in the absence of effective therapy the cells can become reactivated and cause recrudescent viraemia. A number of assays have been developed in an attempt to both quantify and improve our understanding of the reservoir. However...

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Division:
MSD
Department:
NDM
Oxford college:
St Cross College
Role:
Author

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Supervisor
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Examiner
Role:
Examiner
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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