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Journal article

Association of low‐activity ALDH2 and alcohol consumption with risk of esophageal cancer in Chinese adults: A population‐based cohort study

Abstract:

Existing evidence remains inconclusive as to how the association between inactive ALDH2 and esophageal cancer (EC)depends on alcohol consumption. The study is based on the China Kadoorie Biobank cohort, with 10 years follow-up of 0.5million adults aged 30–79 years. ALDH2 activity was assessed by both self-reported flushing response and Glu504Lys(rs671 G>A) polymorphism. Among both male and female participants who consumed alcohol less than weekly(n569,519; 211 EC cases), low active or inac...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/ijc.31566

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Population Health; Clinical Trial Service Unit
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Population Health; Clinical Trial Service Unit
Role:
Author
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National Natural Science Foundation of China More from this funder
National Key Research and Development Program of China More from this funder
Chinese Ministry of Science and Technology More from this funder
Kadoorie Charitable Foundation More from this funder
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Publisher:
Wiley Publisher's website
Journal:
International Journal of Cancer Journal website
Volume:
143
Issue:
7
Pages:
1652-1661
Publication date:
2018-06-11
Acceptance date:
2018-04-23
DOI:
EISSN:
1097-0215
ISSN:
0020-7136
Keywords:
Pubs id:
pubs:844226
UUID:
uuid:abbb5fd2-dd3f-4b53-ada2-db9c3742f512
Local pid:
pubs:844226
Deposit date:
2018-04-25

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