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Thesis

Pre-clinical development of viral vectored transmission-blocking malaria vaccines

Abstract:

Malaria transmission-blocking vaccine candidate antigens have been developed to induce antibodies using different delivery systems, mainly protein-in-adjuvant formulations, independently in various laboratories giving varied transmission-blocking activity (TBA). However, only one candidate antigen has been tested in clinical trials. In order to advance the most efficacious target(s) for possible clinical development, a rank order of the leading antigens based on TBA in a head-to-head compa...

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Research group:
Jenner Institute
Oxford college:
Wolfson College
Role:
Author

Contributors

Division:
MSD
Department:
NDM
Role:
Supervisor
Division:
MSD
Department:
NDM
Role:
Supervisor
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
Subjects:
UUID:
uuid:a5610025-28e1-433f-9487-aaa1f6d641a0
Local pid:
ora:10012
Deposit date:
2015-02-11

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