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Impact of obesity and SARS-CoV-2 infection: implications for host defence - a living review

Abstract:

The role of obesity in the pathophysiology of respiratory virus infections has become particularly apparent during the current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, where obese patients are twice as likely to suffer from severe coronavirus disease 2019 (COVID-19) than healthy weight individuals. Obesity results in disruption of systemic lipid metabolism promoting a state of chronic low-grade inflammation. However, it remains unclear how these underlying metabo...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1093/oxfimm/iqab001

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Oxford college:
St Hilda's College
Role:
Author
ORCID:
0000-0002-3415-3449

Contributors

Wellcome Trust More from this funder
Publisher:
Oxford University Press Publisher's website
Journal:
Oxford Open Immunology Journal website
Volume:
2
Issue:
1
Place of publication:
England
Publication date:
2021-01-21
Acceptance date:
2021-01-05
DOI:
EISSN:
2633-6960
Pmid:
34192269
Language:
English
Keywords:
Pubs id:
1164009
Local pid:
pubs:1164009
Deposit date:
2021-11-05

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