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LGI1-antibody associated epilepsy successfully treated in the outpatient setting

Abstract:

We report six patients with anti-LGI1 associated epilepsy. Two patients presented with new-onset generalized tonic-clonic seizures, four developed faciobrachial dystonic seizures and two piloerection. All patients had significant cognitive complaints at the time of diagnosis. All patients described seizure reduction during the first week of carbamazepine, and seizure freedom was obtained at a median of 13 days (range 7–22), sustained after the initiation of immunosuppression. Median time from...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Oxford college:
St Hilda's College
Role:
Author
ORCID:
0000-0002-7667-9748
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Publisher:
Elsevier Publisher's website
Journal:
Journal of Neuroimmunology Journal website
Volume:
345
Article number:
577268
Publication date:
2020-05-23
Acceptance date:
2020-05-19
DOI:
EISSN:
1872-8421
ISSN:
0165-5728
Pubs id:
1108395
Local pid:
pubs:1108395

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