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Comparative risk of acute myocardial infarction for anti-osteoporosis drugs in primary care: a meta-analysis of propensity-matched cohort findings from the UK Clinical Practice Research Database and the Catalan SIDIAP Database

Abstract:

Summary

The aim of this study was to evaluate the risk of acute myocardial infarction in patients taking osteoporosis medication. Patients were taken from the SIDIAP or CPRD database and were matched using propensity scores. Patients with diabetes and chronic kidney disease taking SERMs were at an increased risk. The results favour the cardiovascular safety of alendronate as a first-line choice for osteoporosis treatment.

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1007/s00198-021-06262-1

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Botnar Research Centre
Role:
Author
ORCID:
0000-0002-2845-5731
Publisher:
Springer Publisher's website
Journal:
Osteoporosis International Journal website
Volume:
33
Issue:
7
Pages:
1579–1589
Publication date:
2022-02-09
Acceptance date:
2022-01-03
DOI:
EISSN:
1433-2965
ISSN:
0937-941X
Language:
English
Keywords:
Pubs id:
1233192
Local pid:
pubs:1233192
Deposit date:
2022-01-21

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