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Journal article

Genetic variation in PLEKHG1 is associated with white matter hyperintensities (n = 11,226)

Abstract:

Objective To identify novel genetic associations with white matter hyperintensities (WMH).

Methods We performed a genome-wide association meta-analysis of WMH volumes in 11,226 individuals, including 8,429 population-based individuals from UK Biobank and 2,797 stroke patients. Replication of novel loci was performed in an independent dataset of 1,202 individuals. In all studies, WMH were quantified using validated automated or semi-automated methods...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1212/WNL.0000000000006952

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Publisher:
American Academy of Neurology Publisher's website
Journal:
Neurology Journal website
Volume:
92
Issue:
8
Pages:
e749-e757
Publication date:
2019-01-18
Acceptance date:
2018-10-15
DOI:
EISSN:
1526-632X
ISSN:
0028-3878
Pmid:
30659137
Source identifiers:
966088
Language:
English
Pubs id:
pubs:966088
UUID:
uuid:9beb7577-6d00-4fec-b9fa-8eddafcb9d4a
Local pid:
pubs:966088
Deposit date:
2019-08-27

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