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Severe eosinophilic asthma treated with mepolizumab stratified by baseline eosinophil thresholds: a secondary analysis of the DREAM and MENSA studies.

Abstract:

Background

Findings from previous studies showed that mepolizumab significantly reduces the rate of exacerbations in patients with severe eosinophilic asthma. To assess the relationship between baseline blood eosinophil counts and efficacy of mepolizumab we did a secondary analysis of data from two studies, stratifying patients by different baseline blood eosinophil thresholds.

Methods

We did a post-hoc analysis of data, which was completed on Sept 25, 2015, from t...

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Publication status:
Published
Peer review status:
Peer reviewed

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Authors


GlaxoSmithKline More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Lancet Respiratory Medicine Journal website
Publication date:
2016-05-01
DOI:
EISSN:
2213-2619
ISSN:
2213-2600
Source identifiers:
623376
Language:
English
Pubs id:
pubs:623376
UUID:
uuid:9767397e-97be-4d77-ad84-988750ea0271
Local pid:
pubs:623376
Deposit date:
2016-05-31

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