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Association between Adult Height and Risk of Colorectal, Lung, and Prostate Cancer: Results from Meta-analyses of Prospective Studies and Mendelian Randomization Analyses

Abstract:

BACKGROUND:Observational studies examining associations between adult height and risk of colorectal, prostate, and lung cancers have generated mixed results. We conducted meta-analyses using data from prospective cohort studies and further carried out Mendelian randomization analyses, using height-associated genetic variants identified in a genome-wide association study (GWAS), to evaluate the association of adult height with these cancers. METHODS AND FINDINGS:A systematic review of prospect...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pmed.1002118

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Publisher:
Public Library of Science Publisher's website
Journal:
PLoS Medicine Journal website
Volume:
13
Issue:
9
Article number:
e1002118
Publication date:
2016-09-06
Acceptance date:
2016-07-28
DOI:
EISSN:
1549-1676
ISSN:
1549-1277
Pmid:
27598322
Source identifiers:
655742
Language:
English
Keywords:
Pubs id:
pubs:655742
UUID:
uuid:953d9edd-0045-4971-9f93-db6d9d0a075d
Local pid:
pubs:655742
Deposit date:
2019-03-14

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