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Thesis

Development of tools to provide prioritisation and guidance in the development of chemical probes and small molecule leads

Abstract:

Experimental methodological developments in measuring protein-ligand interactions for small molecule (<900 Da) drug discovery have led to an influx of data. In some instances this data overload has been overwhelming and can complicate rather than inform decision-making during drug discovery. The focus of this thesis is thus to develop novel methods to contextualise and extract useful information that helps medicinal and computational chemists make sense of available data and improve the...

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author

Contributors

Role:
Supervisor
Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
UUID:
uuid:953c12a4-fe34-4c0f-8485-7296db1d9d07
Deposit date:
2015-10-28

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