Group 2 innate lymphoid cells express functional NKp30 receptor inducing type 2 cytokine production
Group 2 innate lymphoid cells (ILC2) are important in effector functions for eliciting allergic inflammation, parasite defense, epithelial repair, and lipid homeostasis. ILC2 lack rearranged Ag-specific receptors, and although many soluble factors such as cytokines and lipid mediators can influence ILC2, direct interaction of these cells with the microenvironment and other cells has been less explored. Natural cytotoxicity receptors are expressed by subsets of group 1 ILC and group 3 ILC and ...Expand abstract
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- American Association of Immunologists, Inc.
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- Copyright © 2015 by The American Association of Immunologists, Inc.
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