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Group 2 innate lymphoid cells express functional NKp30 receptor inducing type 2 cytokine production

Abstract:

Group 2 innate lymphoid cells (ILC2) are important in effector functions for eliciting allergic inflammation, parasite defense, epithelial repair, and lipid homeostasis. ILC2 lack rearranged Ag-specific receptors, and although many soluble factors such as cytokines and lipid mediators can influence ILC2, direct interaction of these cells with the microenvironment and other cells has been less explored. Natural cytotoxicity receptors are expressed by subsets of group 1 ILC and group 3 ILC and ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.4049/jimmunol.1501102

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
Weatherall Insti. of Molecular Medicine
Role:
Author
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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
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Publisher:
American Association of Immunologists Publisher's website
Journal:
Journal of Immunology Journal website
Volume:
196
Issue:
1
Pages:
45-54
Publication date:
2015-12-18
Acceptance date:
2015-10-20
DOI:
EISSN:
1550-6606
ISSN:
0022-1767
Language:
English
Keywords:
UUID:
uuid:93f07220-b483-4a5a-b361-86267dbf8a69
Deposit date:
2015-11-12

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