Thesis
Examining the relationship between genetic variation at G6PD and severe malaria
- Abstract:
-
Glucose-6-phosphate dehydrogenase (G6PD) deficiency, a common heritable trait whose prevalence mirrors geographic patterns of historic malaria endemicity, is thought to confer a selective advantage owing to partial protection conferred against malaria. Direct evidence supporting this malaria protection hypothesis in the form of clinical association studies remains controversial, however, as conflicting results have been reported with respect to the strength and specificity of a protective ...
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Authors
Contributors
+ Kwiatkowski, DP
Division:
MSD
Department:
NDM
Role:
Supervisor
+ Rockettt, K
Division:
MSD
Department:
NDM
Role:
Supervisor
Funding
Bibliographic Details
- Publication date:
- 2011
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:933063af-9cd9-4f74-94c9-55ef2db28551
- Local pid:
- ora:8719
- Deposit date:
- 2014-07-04
Terms of use
- Copyright holder:
- Shah, SS
- Copyright date:
- 2012
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