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Journal article

A gene signature for selecting benefit from hypoxia modification of radiotherapy for high risk bladder cancer patients

Abstract:

PURPOSE: Hypoxia modification improves overall survival in muscle invasive bladder cancer patients who undergo radiotherapy. There is evidence that hypoxic tumors benefit most from hypoxia modification. The study aimed to identify or derive a hypoxia gene signature that predicts benefit from hypoxia-modifying treatment in bladder cancer.

Experimental Design: Published hypoxia signatures were tested and a new one derived by analyzing bladder cancer transcriptomic data from public data...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1158/1078-0432.CCR-17-0038

Authors


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Funding agency for:
Taylor, J
Grant:
C480/A12328
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Funding agency for:
Eustace, A
Grant:
G0801525
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Funding agency for:
Buffa, F
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Funding agency for:
Buffa, F
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Publisher:
American Association for Cancer Research Publisher's website
Journal:
Clinical Cancer Research Journal website
Volume:
23
Issue:
16
Pages:
4761-4768
Publication date:
2017-04-11
Acceptance date:
2017-04-05
DOI:
EISSN:
1557-3265
ISSN:
1078-0432
Source identifiers:
689680
Language:
English
Keywords:
Pubs id:
pubs:689680
UUID:
uuid:915f3fce-5b99-43e6-bded-f69319711021
Local pid:
pubs:689680
Deposit date:
2017-06-14

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